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Updated: Dec 14, 2025
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Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
Published on: January 29, 2016
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Current perspectives on exercise training in the management of multiple sclerosis
Robert W Motl1, Brian M Sandroff1
1Department of Physical Therapy, University of Alabama at Birmingham , Birmingham, AL, USA.
Expert Review of Neurotherapeutics
|July 16, 2020
Summary
Exercise and physical activity are vital for managing multiple sclerosis (MS). Further research in key areas can improve exercise integration into clinical care for individuals with MS.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Scientific evidence for exercise in multiple sclerosis (MS) management has grown significantly over 25 years.
- Exercise training is a standard recommendation for MS care.
- Opportunities exist to broaden and strengthen research on exercise for MS.
Purpose of the Study:
- To identify and discuss eight emerging research areas for exercise and physical activity in persons with MS.
- To highlight the importance of continued research for clinical translation.
- To provide expert perspectives on future research directions.
Main Methods:
- Literature review and expert consensus.
- Identification of key research themes.
- Synthesis of current knowledge and future directions.
Main Results:
- Eight emerging research areas identified: behavior change interventions, activity continuum research, telerehabilitation, neuroplasticity, outcome heterogeneity, targeted sampling, combined interventions, and multi-site trials.
- These areas represent critical opportunities for advancing exercise science in MS.
- Further research is needed to translate findings into clinical practice.
Conclusions:
- Continued research in the identified areas is essential for optimizing exercise and physical activity interventions for individuals with MS.
- Expanding research will enhance the translation of exercise strategies into routine clinical care.
- Future studies should focus on translating exercise benefits into improved management of MS.
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