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Updated: Dec 14, 2025

Methods of Ex Situ and In Situ Investigations of Structural Transformations: The Case of Crystallization of Metallic Glasses
Published on: June 7, 2018
Crystallographic and spectroscopic characterization of racemic Mosher's Acid
Carolyn Z Savich1, Joseph M Tanski1
1Department of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Abstract:
The title compound, C10H9F3O3, represents the structure of racemic Mosher's Acid (systematic name: 3,3,3-tri-fluoro-2-meth-oxy-2-phenyl-propanoic acid), a carb-oxy-lic acid that when resolved can be employed as a chiral derivatizing agent. The compound contains a carb-oxy-lic acid group, a meth-oxy group and a tri-fluoro-methyl substituent on an asymmetric benzylic carbon atom. The two independent mol-ecules in the asymmetric unit form a non-centrosymmetric homochiral dimer via inter-molecularly hydrogen-bonded head-to-tail dimers with graph-set notation R 2 2(8) and donor-acceptor hydrogen-bonding distances of 2.6616 (13) and 2.6801 (13) Å.
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