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Related Experiment Video

Updated: Dec 14, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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His bundle lead placement: Is His bundle captured?

Ronpichai Chokesuwattanaskul¹, Krit Jongnarangsin¹

¹Division of Cardiac Electrophysiology, University of Michigan Health Care, Ann Arbor, Michigan.

Pacing and Clinical Electrophysiology : PACE

|July 23, 2020

Summary

This summary is machine-generated.

This study explores His bundle pacing in a patient with heart block. Analysis of intracardiac electrograms suggests His bundle capture may not have occurred, highlighting the complexity of pacing technologies.

Keywords:

His bundle pacing infra-Hisian conduction delay

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Area of Science:

Cardiology
Electrophysiology
Medical Devices

Background:

A 59-year-old female received a dual-chamber pacemaker for intermittent complete heart block.
Baseline electrocardiogram revealed normal sinus rhythm with first-degree atrioventricular (AV) block and right bundle branch block.

Observation:

A His bundle lead was implanted, and intracardiac electrograms showed atrial-His and His-ventricular intervals of 186 ms and 110 ms, respectively.
Pacing from the His bundle lead with decreasing output did not result in significant QRS morphology changes.

Findings:

The study questions whether His bundle capture was achieved despite lead placement.
Intracardiac electrogram analysis revealed specific conduction intervals within the His Purkinje system.

Implications:

Understanding His Purkinje system physiology is crucial for advanced pacing techniques.
This case highlights the challenges and diagnostic considerations in His bundle pacing and conducting system pacing technologies.