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Three-year Survival of Women with Breast Cancer in Basrah, Iraq
Jasim N Al-Asadi1, Sundus M Al-Mayah2
1Department of Family and Community Medicine, College of Medicine, University of Basrah, Basrah,Iraq.
Insights
The three-year survival rate for breast cancer patients in Basrah, Iraq, was 83.3%. Advanced tumor stage and poorly differentiated tumors were linked to poorer survival outcomes in women with breast cancer.
Area of Science:
- Oncology
- Epidemiology
Background:
- Breast cancer survival rates vary globally, with significant disparities between developed and developing countries.
- Understanding local survival data is crucial for improving patient outcomes in specific regions like Basrah, Iraq.
Purpose of the Study:
- To determine the three-year observed survival rate of women diagnosed with breast cancer in Basrah, Iraq.
- To identify prognostic factors associated with breast cancer survival in this population.
Main Methods:
- Retrospective data collection from the Oncology Center registry in Basrah.
- Inclusion of 605 women diagnosed with breast cancer between 2013-2014, with follow-up until 2017.
- Kaplan-Meier method for survival estimation and Cox regression for prognostic factor analysis.
Main Results:
- The overall three-year observed survival rate was 83.3%.
- 44.1% of patients presented with advanced tumor stages (III and IV).
- Late stage (Stage IV vs. I) and poorly differentiated tumors were significantly associated with reduced survival (HR > 4).
Conclusions:
- The three-year survival rate in Basrah is comparable to developing countries but lower than in developed nations.
- Advanced tumor stage and poor tumor differentiation are significant predictors of decreased survival in Iraqi women with breast cancer.
Objectives:
We sought to determine the overall observed three-year survival rate of women with breast cancer in Basrah, Iraq, and investigate the associated factors.
Methods:
Data was collected retrospectively from the Oncology Center registry in Basrah, all newly diagnosed women with breast cancer between 1 January 2013 and 31 December 2014 were included and followed-up until 31 December 2017. We used the Kaplan-Meier method to estimate the overall survival rates. Cox regression analysis was used to investigate the association between survival and prognostic factors.
Results:
A total of 605 women who were diagnosed with breast cancer during 2013- 2014 were included in the study, 44.1% had advanced tumor stages (stage III and IV). The overall observed three-year survival rate was 83.3%. Cox regression analysis showed that late stage (stage IV vs. stage I hazard ratio (HR) = 4.65; 95% confidence interval (CI): 3.28-7.81) and grade (poorly vs. well differentiated HR = 4.10; 95% CI: 3.01-6.82) were significantly associated with poor survival.
Conclusions:
The overall observed survival rate of women with breast cancer in Basrah was comparable to that reported for developing countries, but it is poorer than that of developed countries. Advanced stage and poorly differentiated tumors were significant predictors of poor survival.
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