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Updated: Dec 13, 2025

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Guidelines on Optical Coherence Tomography Angiography Imaging: 2020 Focused Update
Enrico Borrelli1, Mariacristina Parravano2, Riccardo Sacconi1
1Ophthalmology Department, San Raffaele University Hospital, Milan, Italy.
Optical coherence tomography angiography (OCTA) advances understanding of eye blood vessels. This review covers OCTA principles, retinal and choroidal vessel applications, and 3D visualization updates.
Area of Science:
- Ophthalmology
- Medical Imaging
- Vascular Biology
Background:
- Optical coherence tomography angiography (OCTA) is a revolutionary imaging technique.
- It provides non-invasive visualization of ocular vasculature.
- Previous guidelines were published in 2019.
Purpose of the Study:
- To review the fundamental principles of OCTA.
- To discuss the application of OCTA in studying retinal and choroidal vessels.
- To highlight recent advancements in OCTA technology, including 3D visualization.
Main Methods:
- Review of existing literature and guidelines.
- Focus on updates since the 2019 publication.
- Emphasis on 2020 findings and technological progress.
Main Results:
- OCTA significantly enhances the study of retinal and choroidal vasculature.
- Three-dimensional (3D) OCTA visualization offers new insights.
- The review consolidates current knowledge and guidelines.
Conclusions:
- OCTA is an indispensable tool for ophthalmologists and researchers.
- Continued advancements in OCTA technology promise further discoveries.
- This review serves as an updated resource for OCTA applications.
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