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Updated: Dec 11, 2025
Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research
Published on: June 8, 2022
An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence
Junjie Chen1, Yichang Fang, Lihe Sun
1State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
Abstract:
A probe has been developed for imaging alcoholic liver injury through detecting the overexpressed cytochrome P450 reductase in hypoxia in the hepatic region. Upon response to the enzyme, the activated probe displays turn-on fluorescence and near-infrared absorption and generates prominent optoacoustic signals.
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