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Renin-Angiotensin-Aldosterone Inhibitors and COVID-19

Irina Benenson, Frederick Andrew Waldron

    The Journal for Nurse Practitioners : JNP
    |August 25, 2020
    PubMed

    Insights

    Renin-angiotensin-aldosterone system (RAAS) blockers do not worsen COVID-19 outcomes. Continued use of RAAS blockers is recommended to prevent cardiovascular complications, especially in stable patients.

    Area of Science:

    • Cardiology
    • Infectious Diseases
    • Pharmacology

    Background:

    • Concerns exist regarding renin-angiotensin-aldosterone system (RAAS) blockers and COVID-19 susceptibility.
    • RAAS blockers are crucial for managing various cardiovascular conditions.

    Purpose of the Study:

    • To evaluate the impact of RAAS blockers on COVID-19 course.
    • To provide evidence-based recommendations on RAAS blocker use during the pandemic.

    Main Methods:

    • Review of existing literature and clinical data.
    • Analysis of patient outcomes based on RAAS blocker treatment.

    Main Results:

    • No evidence suggests RAAS blockers worsen COVID-19 severity.
    • Discontinuation of RAAS blockers may lead to worsening of cardiovascular comorbidities.

    Conclusions:

    • RAAS blockers should be continued in patients with stable conditions.
    • The benefits of RAAS blockers in managing cardiovascular disease outweigh theoretical risks associated with COVID-19.

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