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Arrhythmia in COVID-19

Savalan Babapoor-Farrokhran1, Roozbeh Tarighati Rasekhi2, Deanna Gill3

  • 1Department of Medicine, Division of Cardiology, Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141 USA.

SN Comprehensive Clinical Medicine
|August 25, 2020
PubMed

Insights

COVID-19 (coronavirus disease 2019) can cause cardiac complications, including arrhythmias. Myocardial inflammation from SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) infection may lead to heart rhythm disturbances.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Virology

Background:

  • The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has led to widespread health concerns.
  • Cardiac complications are increasingly recognized in patients with coronavirus disease 2019 (COVID-19).
  • Arrhythmias represent a significant cardiac manifestation of COVID-19.

Purpose of the Study:

  • To review the current understanding of arrhythmia manifestations in COVID-19 patients.
  • To explore the potential mechanisms linking SARS-CoV-2 infection to cardiac arrhythmias.
  • To consolidate knowledge on the electrophysiological impact of COVID-19 on the heart.

Main Methods:

  • Literature review of studies on COVID-19 and cardiac complications.
  • Analysis of reported cases and clinical data regarding arrhythmias in COVID-19.
  • Synthesis of evidence on myocardial inflammation and cardiac remodeling in SARS-CoV-2 infection.

Main Results:

  • COVID-19 is associated with various cardiac complications, including myocarditis, heart failure, and acute coronary syndromes.
  • Arrhythmias are a prominent complication, observed in patients with and without pre-existing cardiovascular disease.
  • Viral-induced myocardial inflammation and subsequent remodeling are proposed mechanisms for arrhythmia development.

Conclusions:

  • Arrhythmias are a significant concern in the context of COVID-19.
  • Understanding the mechanisms of SARS-CoV-2-related arrhythmias is crucial for patient management.
  • Further research is needed to fully elucidate the link between COVID-19 and cardiac electrophysiology.

Keywords:
ArrhythmiasAtrial fibrillationCoronavirus disease 2019Middle east respiratory syndromeQT prolongationSevere acute respiratory syndromeSinus bradycardiaSinus tachycardiaTorsade de pointesVentricular arrhythmiasVentricular fibrillationVentricular tachycardiaViral infection

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