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Published on: December 15, 2023
; RESULTS OF RESECTION METHODS OF TREATMENT IN PATIENTS WITH GIANT PYLORODUODENAL ULCERS COMPLICATED BY PERFORATION
A Kosenkov1, E Stoliarchuk1, E Belykh1
11Sechenov First Moscow State Medical University, Moscow, Russian Federation.
This study on gastric resection for ulcers found that while early complications like stomach stump dysfunction and cardiovascular issues occurred in over half of patients, long-term results showed improved quality of life and no ulcer recurrence.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Clinical Medicine
Background:
- Peptic ulcer disease remains a significant cause of morbidity and mortality.
- Surgical intervention, including gastric resection, is a critical treatment option for complicated peptic ulcers.
- Evaluating the outcomes of different gastric resection techniques is essential for optimizing patient care.
Purpose of the Study:
- To analyze the immediate and long-term outcomes of various gastric resection methods for peptic ulcer disease.
- To compare the complication rates and functional results of standard gastric resection versus pylorobulbar resection with vagotomy.
- To assess the impact of surgical interventions on patient quality of life.
Main Methods:
- Retrospective analysis of 35 patients undergoing gastric resection between 2000 and 2019.
- Categorization of surgeries into standard gastric resection (Billroth-II) and pylorobulbar resection (Billroth-I) with vagotomy.
- Evaluation of early postoperative complications, including cardiovascular, respiratory, and gastrointestinal issues.
- Assessment of long-term results, focusing on functional disorders, ulcer recurrence, and quality of life.
Main Results:
- Early postoperative complications occurred in 51.4% of patients, with significant rates of stomach stump evacuation dysfunction (22.8%).
- Cardiovascular and respiratory complications were noted, alongside a 5.7% rate of suture failure.
- Mortality was 22.7%, primarily in patients undergoing urgent surgery for perforation or bleeding.
- Long-term follow-up revealed a decrease in post-gastric resection and post-vagotomy disorders, with no ulcer recurrence and satisfactory quality of life.
Conclusions:
- Gastric resection for peptic ulcer disease is associated with considerable early complications but offers favorable long-term outcomes.
- Standard gastric resection and pylorobulbar resection with vagotomy can lead to good functional results and improved quality of life in the long term.
- Careful patient selection and surgical technique are crucial for minimizing complications and ensuring positive long-term results.
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