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Technical Note: Scintillation markers for real-time visual source tracking during skin high dose rate brachytherapy
Elizabeth Huynh1, Mandar S Bhagwat2
1Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Medical Physics
|September 23, 2020
Summary
Scintillation markers provide real-time visual verification for high dose rate (HDR) brachytherapy, reducing errors in catheter connections and improving patient safety during surface applicator treatments.
Area of Science:
- Medical Physics
- Radiation Oncology
- Materials Science
Background:
- High dose rate (HDR) brachytherapy treatments are susceptible to errors from manual data entry and hardware connections, particularly with complex surface applicators.
- These errors can lead to treatment misadministration and compromise patient safety.
- Quality assurance (QA) in HDR brachytherapy requires robust methods to prevent such errors.
Purpose of the Study:
- To develop and evaluate a simple, real-time visual verification method for HDR surface brachytherapy.
- To reduce manual errors in catheter length entry and hardware connections.
- To enhance patient safety by improving QA measures.
Main Methods:
- Fabricated cerium-doped lutetium yttrium orthosilicate (LYSO) scintillation markers (5-mm diameter) embedded in a polymer.
- Attached markers to a Freiburg flap applicator to verify catheter-transfer tube connections using an 192 Ir source.
- Placed markers along the target periphery to confirm source reach and visually tracked the HDR source via marker illumination, even through thermoplastic material.
Main Results:
- Scintillation markers emitted intense blue light when irradiated by the HDR source, confirming its presence in the correct catheter.
- The visual signal was discernible even with thermoplastic material overlaying the applicator.
- Light intensity crosstalk between adjacent catheters was less than 50% of the maximum.
Conclusions:
- Developed scintillation markers and paint enable successful visual tracking of the HDR source in surface brachytherapy.
- Direct source visualization allows real-time catheter verification and confirmation of superficial target coverage, preventing medical events.
- This method can be readily integrated into existing QA programs.

