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Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute

Giuseppe Sciumè1, Yohei Mikami2, Dragana Jankovic3

  • 1Lymphocyte Cell Biology Section, Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Molecular Medicine, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia - Fondazione Cenci-Bolognetti, 00185 Rome, Italy.

Immunity
|October 3, 2020
PubMed

Keywords:
T-betToxoplasma Gondii infectionde novo enhancersinnate lymphoid cellslineage defining transcription factorsnatural killer cellspoised enhancerssignal regulated transcription factorssignal transducer and activator of transcription (STAT) proteinsuper-enhancers

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