Related Experiment Video
Updated: Dec 5, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Malignant onychopapilloma
Eckart Haneke1,2,3,4, Matilde Iorizzo5, Max Gabutti1
1Department of Dermatology, Inselspital, University of Bern, Bern, Switzerland.
Onychopapilloma is a nailbed lesion diagnosed clinically. A rare malignant case developed pain, requiring surgical removal and histopathological analysis.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Onychopapilloma is a recognized nailbed lesion.
- Its typical presentation allows for clinical diagnosis.
- The lesion extends from the distal matrix to the hyponychium.
Observation:
- A case of onychopapilloma presented with pain.
- The pain led to complete surgical excision of the lesion.
Findings:
- Histopathological examination confirmed a malignant onychopapilloma.
- This highlights the potential for malignancy in this lesion.
Implications:
- The differential diagnosis of onychopapilloma requires careful consideration.
- Early recognition and diagnosis are crucial for patient outcomes.
- Further research into malignant onychopapilloma is warranted.
More Related Videos
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
09:33Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
Published on: August 25, 2023
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
Abnormal Proliferation
Induced Pluripotent Stem Cells
Somatic...
Cancer
Cancer Cell Migration through Invadopodia