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Leaf Spray Mass Spectrometry: A Rapid Ambient Ionization Technique to Directly Assess Metabolites from Plant Tissues
Published on: June 21, 2018
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USB-Powered Coated Blade Spray Ion Source for On-Site Testing Using Transportable Mass Spectrometry
Josha Jager1, Arjen Gerssen1, Janusz Pawliszyn2
1Wageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, 6700 AE Wageningen, The Netherlands.
Journal of the American Society for Mass Spectrometry
|October 21, 2020
Summary
A new, inexpensive USB-powered coated blade spray (CBS) ion source enables on-site food analysis using mass spectrometry (MS). This simplified device, compatible with smartphones, offers potential for rapid food safety testing.
Area of Science:
- Analytical Chemistry
- Mass Spectrometry
- Food Safety
Background:
- On-site food analysis via mass spectrometry (MS) necessitates miniaturized components.
- Current MS systems often lack portability and require complex infrastructure.
Purpose of the Study:
- To develop a simplified, portable, and inexpensive ion source for on-site MS analysis.
- To demonstrate the utility of the developed ion source for food safety applications.
Main Methods:
- Development of a coated blade spray (CBS) ion source powered by USB On-The-Go devices.
- Integration of the USB-CBS device with single-quadrupole and triple-quadrupole MS systems.
- Analysis of banned veterinary drugs (β-agonists, sulfonamides) in food samples.
Main Results:
- The USB-CBS device successfully generated high voltage for ionization.
- Analyte enrichment via solid-phase microextraction (SPME) and direct-spray ionization were achieved.
- Detection of target veterinary drugs demonstrated the device's potential for food safety screening.
Conclusions:
- The developed USB-CBS ion source is a simplified, low-cost, and universal solution for MS-based analysis.
- This technology holds significant promise for on-site food safety, environmental, biomedical, and forensic testing.
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