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Published on: April 13, 2018
[A CASE REPORT: EOSINOPHILIC CYSTITIS PRESENTED WITH DEEP VEIN THROMBOSIS]
Michikata Hayashida1, Akihiro Yano1, Kiichi Hagiwara1
1Department of Urology, Toranomon Hospital.
A 76-year-old man with deep vein thrombosis (DVT) developed eosinophilic cystitis, presenting with bladder masses and blood abnormalities. Prompt treatment with prednisolone resolved the condition and prevented recurrence.
Area of Science:
- Urology
- Hematology
- Pathology
Context:
- A 76-year-old male patient with a history of deep vein thrombosis (DVT) on anticoagulation presented with gross hematuria.
- Initial investigations revealed peripheral eosinophilia and thrombocytopenia, alongside eosinophils in urine cytology.
- Cystoscopy identified diffuse bladder masses with friable mucosa, and MRI suggested potential muscle invasion.
Purpose:
- To report a rare case of eosinophilic cystitis presenting with bladder masses.
- To highlight the diagnostic challenges and successful management of this condition.
- To underscore the importance of considering eosinophilic infiltration in patients with hematuria and blood count abnormalities.
Summary:
- Histopathological examination of resected bladder masses confirmed eosinophilic infiltration of the bladder wall stroma without malignancy, leading to a diagnosis of eosinophilic cystitis.
- The patient received a course of prednisolone for eosinophilic cystitis.
- Treatment resulted in the prompt resolution of eosinophilia, thrombocytopenia, and disappearance of bladder masses.
Impact:
- This case demonstrates that eosinophilic cystitis can manifest as bladder masses, mimicking malignancy.
- Successful treatment with corticosteroids highlights their efficacy in managing eosinophilic cystitis.
- The resolution of DVT symptoms and absence of recurrence suggest a potential link or successful co-management.
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