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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Asthma-IV: Diagnostic and Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Related Experiment Video

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Managing chronic rhinosinusitis in severe asthma.

Uma S Ramaswamy1, Vijay A Patel, Stella E Lee

  • 1Division of Sino-nasal Disorders and Allergy, Department of Otolaryngology-Head & Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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Severe asthma and chronic rhinosinusitis (CRS) often coexist, sharing linked airway inflammation. Understanding their relationship is key to improving patient outcomes and quality of life.

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Area of Science:

  • Respiratory Medicine
  • Immunology

Background:

  • Over 50% of severe asthma patients also have chronic rhinosinusitis (CRS).
  • Upper and lower airways exhibit interconnected pathophysiologic mechanisms despite distinct functions.
  • Nasal polyp severity in CRS correlates with asthma severity, and vice versa.

Purpose of the Study:

  • To clarify the relationship between severe asthma and chronic rhinosinusitis.
  • To summarize current management strategies for patients with both conditions.

Main Methods:

  • Review of current literature on asthma and CRS.
  • Analysis of shared inflammatory pathways and clinical correlations.

Main Results:

  • Advances in evaluation and treatment for co-existing CRS and asthma.
  • Inflammatory endotypes common to both conditions are being identified.

Conclusions:

  • CRS significantly impacts quality of life; treatments aim to improve symptoms and address immune dysfunction.
  • Multidisciplinary management is essential for patients with CRS and severe asthma.
  • Further real-world studies are needed to optimize treatment algorithms.