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Takotsubo Endocrinopathy.

Sanjay Kalra1, Om J Lakhani2, Sandeep Chaudhary3

  • 1Department of Endocrinology, Bharti Hospital, Karnal, India.

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|October 29, 2020
PubMed
Summary
This summary is machine-generated.

Takotsubo cardiomyopathy (TCMP), often seen in post-menopausal women, may stem from endocrine disorders. This review explores the link between endocrine issues and TCMP, suggesting

Keywords:
Acute heart failureacute coronary syndromeadrenal glandscardiac autonomic neuropathydiabetespheochromocytomathyroid

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Area of Science:

  • Endocrinology
  • Cardiology
  • Internal Medicine

Background:

  • Takotsubo cardiomyopathy (TCMP) mimics acute coronary syndrome, frequently affecting post-menopausal women.
  • The underlying cause of TCMP is not fully understood, but an endocrine basis is increasingly suspected.
  • Current understanding suggests a potential link between hormonal imbalances and the development of TCMP.

Purpose of the Study:

  • To review endocrine disorders associated with Takotsubo cardiomyopathy.
  • To elucidate the pathogenetic mechanisms linking endocrine dysfunction to TCMP.
  • To highlight the potential utility of the term 'takotsubo endocrinopathy'.

Main Methods:

  • Literature review of studies on Takotsubo cardiomyopathy and endocrine disorders.
  • Analysis of pathogenetic pathways connecting hormonal imbalances to cardiac dysfunction.
  • Examination of clinical presentations and diagnostic considerations.

Main Results:

  • Several endocrine disorders are identified as potential contributors to TCMP.
  • Pheochromocytoma-associated cardiomyopathy closely mimics TCMP and warrants exclusion.
  • Oestrogen deficiency is explored as a significant factor in TCMP pathogenesis.

Conclusions:

  • Endocrine factors play a crucial role in the development of Takotsubo cardiomyopathy.
  • The term 'takotsubo endocrinopathy' may offer a more accurate description.
  • Involvement of an endocrinologist is vital for TCMP management.