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Sialendoscopy and Sjogren's Disease: A Systematic Review
Kimberly K Coca1, M Boyd Gillespie1, Nicholas A Beckmann1
1Department of Otolaryngology-Head and Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, U.S.A.
The Laryngoscope
|November 3, 2020
Summary
Therapeutic sialendoscopy offers temporary symptom relief for Sjogren's syndrome (SS) patients, with studies suggesting 90%-99% improvement. Further research is needed for consistent treatment protocols.
Area of Science:
- Otolaryngology
- Rheumatology
- Minimally Invasive Surgery
Background:
- Sjogren's syndrome (SS) is an autoimmune disorder affecting salivary glands.
- Therapeutic sialendoscopy is an emerging treatment for SS-related salivary dysfunction.
Purpose of the Study:
- To systematically review and estimate treatment outcomes for Sjogren's syndrome patients undergoing therapeutic sialendoscopy.
- To assess the efficacy of sialendoscopy in improving patient symptoms.
Main Methods:
- Systematic review of PubMed, Scopus, and Cochrane databases up to August 2020.
- Inclusion of English-language studies with multiple human patients, following PRISMA guidelines.
- Qualitative pooling of symptom improvement outcomes from six included studies.
Main Results:
- Six studies involving 125 SS patients and 25 controls were analyzed.
- Symptom improvement was observed in 90% to 99% of patients, suggesting temporary relief.
- Significant diversity in outcome reporting tools was noted across studies.
Conclusions:
- Sialendoscopy shows promise for treating salivary gland disease in Sjogren's syndrome.
- Larger studies with standardized outcome measures are necessary to validate findings.
- Further research is required to establish consistent therapeutic protocols.
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