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Updated: Nov 27, 2025
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An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
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[Squamous Cell Papilloma of the Urinary Bladder]
Kazushiro Takei1, Yoshiro Otsuki2
1The Department of Urology, Seirei Fuji Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|December 3, 2020
Summary
This case report details an extremely rare urinary bladder squamous cell papilloma in a 76-year-old woman. The tumor recurred post-surgery but is currently stable during follow-up.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Squamous cell papilloma of the urinary bladder is an exceedingly rare condition.
- Only 15 cases have been documented in existing literature.
- This report presents a unique case in a 76-year-old female patient.
Observation:
- A 76-year-old woman presented with multifocal urinary bladder tumors discovered incidentally.
- Cystoscopy revealed a 3 cm nonpapillary, whitish plaque-like tumor.
- Initial urinalysis and urine cytology showed no abnormalities.
Findings:
- Histopathology confirmed a papillary noninvasive squamous cell tumor with significant keratinization.
- Tumor cells lacked nuclear atypia and koilocytotic changes.
- Immunohistochemistry was negative for p16 and p53, aiding diagnosis.
Implications:
- This case expands the understanding of rare bladder neoplasms.
- The tumor's recurrence highlights the need for vigilant follow-up.
- Further research may elucidate the specific etiology and optimal management strategies.
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