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Current concepts and treatment of hyperprolactinemia
1Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk.
Obstetrics and Gynecology Clinics of North America
|December 1, 1987
Summary
Hyperprolactinemia, or high prolactin levels, may indicate central abnormalities. Medical treatment with bromocriptine is effective and safe for managing elevated prolactin.
Area of Science:
- Endocrinology
- Reproductive Health
- Neuroendocrinology
Background:
- Hyperprolactinemia is characterized by elevated prolactin levels in women.
- Elevated prolactin may suggest underlying central nervous system abnormalities, particularly involving the pituitary gland.
Purpose of the Study:
- To provide insight into potential central abnormalities associated with hyperprolactinemia in women.
- To outline appropriate diagnostic and therapeutic strategies for managing elevated prolactin levels.
Main Methods:
- Evaluation of the pituitary gland through appropriate testing.
- Concurrent assessment of thyroid function.
- Clinical assessment to guide treatment decisions.
Main Results:
- Medical management, specifically with bromocriptine, is often advantageous for treating high prolactin levels.
- Bromocriptine demonstrates long-term effectiveness and a favorable safety profile.
Conclusions:
- Elevated prolactin levels in women warrant comprehensive evaluation of the pituitary and thyroid functions.
- Bromocriptine is a safe and effective therapeutic option for managing hyperprolactinemia.