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Related Experiment Videos

Classification of the legionellae.

D J Brenner1

  • 1Molecular Biology Laboratory, Centers for Disease Control, Atlanta, GA 30333.

Seminars in Respiratory Infections
|December 1, 1987
PubMed
Summary
This summary is machine-generated.

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This review details the classification and identification of Legionella species, including Legionella pneumophila, the cause of legionnaires

Area of Science:

  • Microbiology
  • Bacteriology
  • Taxonomy

Background:

  • The Legionellaceae family and Legionella genus encompass numerous species, serogroups, and strains.
  • Legionella pneumophila was first identified following the 1976 Philadelphia outbreak of legionnaires' disease.
  • Several outbreaks preceded the 1976 event, leading to the isolation of three Legionella species before 1976.

Purpose of the Study:

  • To review the classification and identification of known Legionella species and serogroups.
  • To summarize the historical events leading to the discovery and classification of Legionella.
  • To discuss current challenges in Legionella identification and classification.

Main Methods:

  • Phenotypic characterization: growth requirements, media, biochemical tests, fatty acids, quinones, DNA G+C content.

Related Experiment Videos

  • Identification techniques: serology, monoclonal antibodies, gene probes.
  • Taxonomic analysis: DNA hybridization for species-level classification.
  • Main Results:

    • Detailed descriptions of 23 described and 11 unnamed Legionella species, and 49 serogroups.
    • Information provided for each species: name origin, isolation source/location, disease association, type strain, isolator.
    • Evidence supports the classification of all species within a single genus and family.

    Conclusions:

    • Comprehensive overview of Legionella taxonomy, identification, and classification.
    • Highlights difficulties in precise species-level identification and genus-level classification.
    • Provides a foundational resource for understanding Legionella.