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[Zoster disease after Shingrix vaccination].

D Kohn1, T Wetzig

  • 1Klinik für Dermatologie, Dermatochirurgie und Allergologie, Asklepios Klinik Weißenfels, Naumburger Str. 76, 06667, Weißenfels, Deutschland. d.kohn@asklepios.com.

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Summary
This summary is machine-generated.

Shingrix, a recombinant adjuvant subunit vaccine, is approved for preventing zoster and postherpetic neuralgia in adults 60 and older. Monitor for zoster disease if bullous lesions appear post-vaccination.

Keywords:
Bullous skin lesionsInactivated vaccinesPostherpetic neuralgiaShinglesUnexpected side effects

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Area of Science:

  • Vaccinology
  • Immunology
  • Dermatology

Background:

  • Shingrix is a recombinant adjuvant subunit vaccine.
  • It is approved in Germany for preventing zoster (shingles) and postherpetic neuralgia in adults aged 60 years and older.

Purpose of the Study:

  • To inform healthcare providers about Shingrix vaccine indications and potential adverse events.
  • To emphasize the importance of considering zoster disease in cases of bullous skin lesions post-vaccination.

Main Methods:

  • Review of vaccine approval information and clinical guidelines.
  • Clinical observation and reporting of adverse events.

Main Results:

  • Shingrix is indicated for zoster prevention in adults aged ≥60 years.
  • Bullous skin lesions after Shingrix vaccination may indicate zoster disease.

Conclusions:

  • Healthcare providers should be vigilant for zoster manifestations in vaccinated individuals presenting with specific skin lesions.
  • Reporting unexpected side effects to the Drug Commission of the German Medical Association is crucial for vaccine safety monitoring.