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Prevalence of control groups in cardiovascular clinical trials: An analysis of ClinicalTrials.gov from 2009 through

Alexander R Zheutlin1, David J Caldwell2, Jad Al Danaf3

  • 1Department of Internal Medicine, University of Utah, Salt Lake City, UT, Seattle, WA.

American Heart Journal
|December 21, 2020
PubMed

Insights

Most cardiovascular clinical trials use a control group for accurate results. Between 2009 and 2019, over 80% of Phase III and IV trials included a control, showing consistent practice.

Area of Science:

  • Cardiovascular Medicine
  • Clinical Research Methodology
  • Evidence-Based Practice

Background:

  • Clinical trials are essential for patient care decisions.
  • Comparing interventions to control groups is crucial for evaluating therapeutic effects and safety.
  • Understanding the use of control groups in cardiovascular trials is important for research integrity.

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