Related Experiment Video
Updated: Nov 23, 2025

Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Published on: June 1, 2022
[ROLE OF FECAL VOLATILE ORGANIC COMPOUNDS IN THE DIAGNOSIS OF BRONCHOPULMONARY DYSPLASIA]
M Syzdykova1, M Morenko1, M Gatauova1
1NAO "Medical University Astana", Nur-Sultan, Kazakhstan.
Abstract:
The aim of the study was to analyze fecal volatile organic compounds in premature babies born with a weight of less than 1,500 grams in order to identify predictors of BPD. The study presents the results of the study in parallel groups, which are represented by premature babies born with a weight of less than 1500 grams. In the course of scientific work, 137 children were examined, from which stool samples were taken on the 14th and 28th days of life to detect VOCs using gas chromatography with mass spectrometry (GC/MS). The Torion T-9 GC / MS was used to separate and identify the VOCs present in the feces of the subjects. After sampling, these children were further divided into two groups: group I (main) - children who realized BPD (n=89) and group II (control) - children who did not realize BPD (n=48). During the study, 28 VOCs were found in the feces of the subjects on the 14th and 28th days of life, among which the three most significant were identified, among them tetradecane, N-nitrosopyrrolidine, and trichloretene.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Serum Laboratory Studies, Stool Test, Breath Test
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...

