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Updated: Nov 21, 2025
Preparing a 68Ga-labeled Arginine Glycine Aspartate RGD-peptide for Angiogenesis
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Biodistribution of 68Ga-NODA-Aminoglucose in Intact and Tumor-Bearing Mice
V K Tishchenko1,2, V M Petriev3,4, A A Mikhailovskaya1
1National Medical Research Centre of Radiology, Ministry of Health of the Russian Federation, Obninsk, Russia.
Abstract:
We studied the biodistribution of 68Ga-NODA-aminoglucose (68Ga-NODA-AG) in normal mice and mice with experimental model of colon adenocarcinoma tumor. It was shown that 68Ga-NODA-aminoglucose was retained in the tumor for 3 h after injection and demonstrated high level of accumulation in the tumor. Rapid clearance of radioactivity from other organs was observed. The results suggest that 68Ga-NODA-aminoglucose is a promising agent for tumor visualization by positron emission tomography.
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