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Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
Published on: June 18, 2014
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Methodology and applications of elemental mapping by laser induced breakdown spectroscopy
A Limbeck1, L Brunnbauer1, H Lohninger1
1TU Wien, Institute of Chemical Technologies and Analytics, Technische Universität Wien, Getreidemarkt 9/164, 1060, Vienna, Austria.
Analytica Chimica Acta
|January 24, 2021
Summary
Laser-Induced Breakdown Spectroscopy (LIBS) is a powerful elemental analysis technique. LIBS imaging offers detailed elemental distribution mapping for diverse scientific applications.
Area of Science:
- Analytical Chemistry
- Spectroscopy
- Materials Science
Background:
- Laser-Induced Breakdown Spectroscopy (LIBS) is an established method for elemental concentration analysis.
- Elemental composition data alone is often insufficient; spatial distribution information is crucial for heterogeneous samples.
Purpose of the Study:
- To review the instrumental requirements for successful LIBS imaging.
- To discuss data processing and multivariate evaluation methods for LIBS imaging data.
- To summarize current literature on LIBS imaging applications across various scientific fields.
Main Methods:
- Review of state-of-the-art and emerging LIBS instrumentation for elemental imaging.
- Discussion of multivariate data analysis and chemometrics for LIBS imaging data evaluation (classification and quantification).
- Comprehensive literature survey of LIBS imaging applications.
Main Results:
- LIBS imaging enables associating elemental composition with spatial coordinates.
- Simultaneous multi-elemental analysis of solids with minimal sample prep and high speed are key advantages.
- The review covers instrumentation, data processing, and diverse applications.
Conclusions:
- LIBS imaging is a valuable technique for detailed elemental distribution analysis.
- Advancements in instrumentation and data processing enhance LIBS imaging capabilities.
- LIBS imaging finds broad applicability in bioimaging, geosciences, cultural heritage, and materials science.
Keywords:
Application examplesData processingElemental imagingLaser induced breakdown spectroscopyTechnical requirementsMore Related Videos
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