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The Effects of Negative Elements in Environment and Cancer on Female Reproductive System
Jiangxue Qu1, Yuehan Li2, Shujie Liao3
1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Abstract:
With the development of human society, factors that contribute to the impairment of female fertility is accumulating. Lifestyle-related risk factors, occupational risk factors, and iatrogenic factors, including cancer and anti-cancer treatments, have been recognized with their negative effects on the function of female reproductive system. However, the exact influences and their possible mechanism have not been elucidated yet. It is impossible to accurately estimate the indexes of female fertility, but many researchers have put forward that the general fertility has inclined through the past decades. Thus the demand for fertility preservation has increased more and more dramatically. Here we described some of the factors which may influence female reproductive system and methods for fertility preservation in response to female infertility.
Insights
Female fertility is declining due to lifestyle, occupational, and iatrogenic factors. This review discusses these influences and highlights the growing need for fertility preservation methods.
Area of Science:
- Reproductive Medicine
- Environmental Health
Background:
- Female fertility impairment is increasing due to societal development.
- Lifestyle, occupational, and iatrogenic factors negatively impact the female reproductive system.
- Cancer treatments are recognized as a significant iatrogenic factor affecting fertility.
Purpose of the Study:
- To review factors contributing to female infertility.
- To discuss the mechanisms influencing female reproductive health.
- To highlight methods for fertility preservation.
Main Methods:
- Literature review of studies on female fertility.
- Analysis of risk factors affecting reproductive function.
- Compilation of current fertility preservation techniques.
Main Results:
- Multiple factors, including lifestyle and medical treatments, impair female fertility.
- The precise mechanisms of these impairments require further investigation.
- There is a documented decline in general female fertility over recent decades.
Conclusions:
- Understanding the multifaceted causes of female infertility is crucial.
- Fertility preservation is increasingly important due to declining fertility rates.
- Further research is needed to elucidate exact mechanisms and optimize preservation strategies.
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