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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
DIAGNOSTICS AND TREATMENT OF GENITAL INVASION CAUSED BY TRICHOMONAS VAGINALIS AND POSSIBLY OTHER RELATED SPECIES
1Ukrainian Military Medical Academy, Kyiv, Ukraine.
Abstract:
Objective - studying species belonging to the causative agents of trichomoniasis of the genitourinary system in patients with sexually transmitted infections and immunodeficiency, assessing efficiency of their treatment. 77 patients with sexually transmitted infections and immunodeficiency were examined using the method of polymerase chain reaction in order to detect trichomonas species. 32 patients were given treatment and immune system indicators dynamics were determined. Trichomonas tenax was detected in 15.5%, Pentatrichomonas hominis - in 22%, Trichomonas vaginalis - in 4.1% of 77 examined patients. The method of combine treatment, providing for consecutive application of anti-protist substances of ornidazole and nifurotel with PROPES® taking smiltaniosly was effective to manage chronic trichomoniasis in 96.9% cases. Normalization of immune system took place. Trichomonias is a widespread disease in patients with sexually transmitted infections and immunodeficiency at the same time (41.6%). Application of the suggested original method allows us to achieve effective cure of chronic genital trichomoniasis caused by its various trichomonas species. Administration of PROPES® could be recommended as combined treatment of trichomoniasis on the background of immunodeficiency.
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