[BIOLOGICAL HERMETICITY, MECHANICAL STRENGTH AND MORPHOLOGICAL CHARACTERISTICS OF ONE-ROW AND TWO-ROW COLON...

Aim - comparison of biological hermeticity, mechanical strength and differences in morphological characteristics of one-row and two-row colon anastomoses. 20 animals were used in the experiment. Rabbits of both sexes aged from 8 months to 1.5 years and weighing from 1.5 to 2.6 kg were used as experimental animals. The animals were divided into experimental and control groups. In the experimental group we used the developed technique of one-row colon anastomosis (CA) formation, in the control group - the traditional two-row CA. Assessment of mechanical strength was performed by using the original method of pneumopression of colon segment with the anastomosis. The biological hermeticity was assessed by culturing flushing water from the anastomosis line to growth medium. The morphological picture was evaluated by microscopy of histological samples from the anastomosis line. The mechanical strength of the one-row anastomosis, compared with the traditional two-row, was higher at each stage of the study, on the first day by 66.3%, the third - 87.6%, the fifth - 76.1%, the seventh - 85.4%. The formation of a one-row CA allowed to achieve biological hermeticity of the anastomosis area in all periods of the early postoperative period, and when using a double-row suture, the anastomosis area became sterile only from 5 day. Morphologically, the picture was characterized by inflammatory processes in the anastomosis area when using the original technique, which were stopped in 3-5 days, and in the control group they persisted for up to 7 days, accompanied by vascular paresis of the intestinal wall, blood stasis and blood clots, with zones of mucosal necrosis at 3 and 5 day of observation.