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Updated: Nov 17, 2025

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
[Multimodal imaging in atypical choroidal nevus]
Ahmed Mahjoub1, Safa Hadj Salah1, Tesnim Mhamdi1
1Service d'Ophtalmologie, Centre Hospitalier Universitaire Farhat Hached de Sousse, Sousse, Tunisie.
Achromic choroidal nevus, a rare lesion, can lead to choroidal neovascularization. Multimodal imaging confirmed this diagnosis in an atypical case, aiding accurate management.
Area of Science:
- Ophthalmology
- Medical Imaging
- Oncology
Background:
- Choroidal nevi are common, benign ocular tumors.
- They are typically asymptomatic and easily diagnosed.
- Complications like macular syndrome can arise from choroidal degeneration or neovascularization.
Observation:
- A female patient presented with an atypical choroidal lesion.
- Diagnostic challenges were present due to the lesion's unusual characteristics.
Findings:
- Multimodal imaging, including clinical examination, ultrasound, fluorescein angiography, and indocyanine green (ICG) angiography, was utilized.
- The combined imaging approach facilitated the diagnosis of an achromic choroidal nevus.
- The nevus was complicated by choroidal neovascularization.
Implications:
- This case highlights the importance of multimodal imaging in diagnosing atypical choroidal lesions.
- Accurate diagnosis of achromic choroidal nevus with neovascularization is crucial for appropriate patient management.
- Early detection and management can prevent vision loss associated with choroidal neovascularization.
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