Nucleic Acid Immunotherapeutics for Cancer

Tingting Shen1, Yu Zhang2, Shurong Zhou3

  • 1Molecular Sciences and Biomedicine Laboratory, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Collaborative Innovation Center for Molecular Engineering and Theranostics, Hunan University, Changsha 410082, China; Department of Pharmaceutics, Center for Pharmaceutical Engineering and Sciences-School of Pharmacy; Massey Cancer Center; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia 23298, United States.

Summary

Nucleic acid therapeutics, like immunostimulatory DNA/RNA and mRNA, are revolutionizing cancer immunotherapy by harnessing the immune system. These agents require chemical modifications and delivery systems for effective cancer treatment.

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