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Related Experiment Video

Updated: Nov 12, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
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Endoscopic Balloon Therapy.

Michael J Klingler1, Matthew Kroh2

  • 1Cleveland Clinic, 9500 Euclid Avenue, Mail Code H18, Cleveland, OH 44195-0001, USA.

The Surgical Clinics of North America
|March 21, 2021
PubMed
Summary
This summary is machine-generated.

Intragastric balloon therapy offers moderate weight loss for individuals with obesity who haven't succeeded with other methods. While generally safe, common issues include intolerance, and long-term weight regain is a concern.

Keywords:
Endoluminal bariatricsEndoscopic bariatricsIntragastric balloon

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Area of Science:

  • Gastroenterology
  • Bariatric Medicine
  • Endoscopic Surgery

Background:

  • Obesity is a complex chronic disease requiring diverse treatment strategies.
  • Intragastric balloon therapy provides a minimally invasive option for weight management.
  • Current guidelines recommend it for patients with moderate obesity unresponsive to conventional therapies.

Purpose of the Study:

  • To evaluate the efficacy and safety of intragastric balloon therapy.
  • To determine typical weight loss outcomes and treatment durations.
  • To identify common adverse events and long-term implications.

Main Methods:

  • Review of intragastric balloon therapy as an endoluminal obesity treatment.
  • Analysis of patient data for moderate obesity (BMI 30-35 kg/m²).
  • Assessment of treatment duration (4-12 months) and weight loss (6-15% TBWL).

Main Results:

  • Effective for patients with moderate obesity who failed other weight loss methods.
  • Achieved 6-15% total body weight loss during 4-12 months of treatment.
  • Rare serious adverse events; common complication is early removal due to intolerance.

Conclusions:

  • Intragastric balloon therapy is a viable option for moderate obesity.
  • Long-term efficacy is limited by potential weight regain after removal.
  • Further research is needed on long-term outcomes and management strategies.