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Updated: Nov 11, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Epidemiology of Melanoma
Nicole L Bolick1, Alan C Geller2
1Harvard T.H. Chan School of Public Health, Kresge Building Room 718, 677 Huntington Ave, Boston, MA 02115, USA; Department of Internal Medicine, East Carolina University/Vidant Medical Center, 600 Moye Boulevard, MA-350, Greenville, NC 27834, USA.
Abstract:
Please add expansion for AL. Melanoma is the most common fatal type of skin cancer and is an important and growing public health problem in the United States, Australia, New Zealand, and Europe. The mortality rate in most of the world has been rising as well, albeit slower than that for incidence. Likely due to the availability of new treatments for stage 4 melanoma, mortality rates in the United States dropped 18% from 2013 to 2016. We further describe trends in melanoma incidence and mortality, review the literature on risk factors, and provide an up-to-date assessment of population-wide screening and some of the inherent concerns.
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