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Related Concept Videos

Photoluminescence: Fluorescence and Phosphorescence01:23

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Photoluminescence is a process where a molecule absorbs light energy and re-emits it in the form of light. This phenomenon occurs when a substance absorbs photons, promoting its electrons to higher energy level excited states, followed by a relaxation process in which the electrons return to their original ground state energy levels and emit light. Photoluminescence is widely observed in various materials, including semiconductors, and organic and inorganic compounds.
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Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
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Updated: Nov 11, 2025

Author Spotlight: Advancing Bioimaging and Therapy with Functional Nanomaterials
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Luminescent Nanomaterials (I).

Hyejin Chang1, Michael M Murata2, Won-Yeop Rho3

  • 1Division of Science Education, Kangwon National University, Chuncheon, Republic of Korea.

Advances in Experimental Medicine and Biology
|March 30, 2021
PubMed
Summary
This summary is machine-generated.

This review covers light-emitting materials for life science imaging and sensing. It details molecular fluorophores and advanced luminescent nanoparticles like quantum dots (QDs) and upconversion nanoparticles (UCNPs).

Keywords:
FluorophoreInorganic nanoparticlesQuantum dot (QD)Upconversion nanoparticles (UCNPs)

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Area of Science:

  • Life Science
  • Materials Science
  • Nanotechnology

Background:

  • Molecular fluorophores and inorganic nanoparticles are crucial for life science imaging and sensing.
  • The development of quantum dots (QDs) has spurred research into other luminescent nanoparticles.
  • Upconversion nanoparticles (UCNPs), metal nanoclusters, and carbon dots are key areas of study.

Purpose of the Study:

  • To review the theoretical background of molecular fluorophores.
  • To describe the development and applications of luminescent inorganic nanoparticles.
  • To present luminescent nanoparticles as versatile sensing and imaging platforms.

Main Methods:

  • Review of theoretical concepts of molecular fluorophores.
  • Description of optical properties and biological applications of various luminescent nanoparticles.
  • Analysis of nanoparticles as sensing and imaging platforms.

Main Results:

  • Established the foundational concepts of molecular fluorophores.
  • Detailed the advancements in quantum dots, upconversion nanoparticles, metal nanoclusters, and carbon dots.
  • Highlighted the potential of these nanomaterials in biological sensing and imaging.

Conclusions:

  • Luminescent nanoparticles offer superior imaging and sensing capabilities in life sciences.
  • Continued development of these nanomaterials promises significant advancements in biological applications.
  • This review provides a comprehensive overview from fundamental principles to technical applications.