Related Experiment Video
Updated: Nov 11, 2025

Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus
Published on: May 31, 2022
Toward a Systematic Nomenclature for (Neo)Lignanamides
Annemiek van Zadelhoff1, Wouter J C de Bruijn1, Zhongxiang Fang2
1Laboratory of Food Chemistry, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
A new systematic nomenclature is proposed for phenylalkenoic acid amides, also known as lignanamides. This naming system enhances clarity and consistency for these bioactive phytochemical dimers and oligomers.
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Bioorganic Chemistry
Background:
- Phenylalkenoic acid amides (phenol amides) are bioactive phytochemicals.
- Their bioactivity can be enhanced through dimerization or oligomerization.
- These compounds are formed by linking a (hydroxy)cinnamic acid derivative to an amine via an amide bond.
Purpose of the Study:
- To address the lack of a systematic nomenclature for phenylalkenoic acid amide dimers and oligomers, termed (neo)lignanamides.
- To propose a new, systematic nomenclature inspired by existing systems for hydroxycinnamic acid dimers and lignin.
- To ensure consistency, future-proofing, and systematic naming of these compounds.
Main Methods:
- Reviewing existing literature on phenylalkenoic acid amides and their dimers.
- Analyzing current naming conventions and their limitations.
- Developing a new nomenclature based on subunit codes, prefixes, and linkage site indicators.
Main Results:
- Identified inconsistencies and lack of systematic approach in current naming of (neo)lignanamides.
- Proposed a new nomenclature system for (neo)lignanamides.
- The proposed system uses three-letter codes for subunits and numbers for linkage points.
Conclusions:
- The proposed systematic nomenclature provides a consistent and future-proof method for naming (neo)lignanamides.
- This new system will improve clarity and facilitate research in the field of bioactive phytochemicals.
- Implementation of this nomenclature will aid in the systematic study and comparison of these compounds.
More Related Videos
07:30A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
Published on: January 21, 2020
08:30Analysis of Neutral Lipid Synthesis in Saccharomyces cerevisiae by Metabolic Labeling and Thin Layer Chromatography
Published on: February 2, 2021
Related Concept Videos
Nomenclature of Aryl and Heterocyclic Amines
Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
Nomenclature of Secondary and Tertiary Amines
Nomenclature of Primary Amines
Nomenclature of Alkanes
The alkane nomenclature considers the length of the carbon chain, the number, and the location of the substituent to arrive at its systematic name. The IUPAC...
IUPAC Nomenclature of Aldehydes