Search research articles

Related Concept Videos

Cerebrospinal Fluid

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparative diagnostic accuracy study of point of care ultrasound techniques for detection of left atrial enlargement by hospital medicine physicians from archived echocardiogram images.

Journal of hospital medicine·2025

Same author

Acute Stroke Diagnosis.

American family physician·2022

Same author

Respiratory Conditions: Upper Respiratory Tract Infections.

FP essentials·2019

Same author

Respiratory Conditions: Lower Respiratory Tract Infections.

FP essentials·2019

Same author

Respiratory Conditions: Interstitial Lung Disease.

FP essentials·2019

Same author

Evaluating Medical Decision-Making Capacity in Practice.

American family physician·2018

Same journal

For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

American family physician·2026

Same journal

Nausea and Vomiting During Pregnancy.

American family physician·2026

Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

American family physician·2026

Same journal

Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

American family physician·2026

Same journal

Overscreening Leads to Overdiagnosis of MASLD.

American family physician·2026

Same journal

Type 2 Diabetes: Outpatient Insulin Management.

American family physician·2026

See all related articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Nov 10, 2025

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Published on: November 29, 2019

Cerebrospinal Fluid Analysis.

Brian Shahan¹, Edwin Y Choi¹, Gilberto Nieves¹

¹Womack Army Medical Center, Fort Bragg, NC, USA.

American Family Physician

|March 31, 2021

Summary

This summary is machine-generated.

Cerebrospinal fluid (CSF) analysis aids in diagnosing central nervous system conditions like meningitis and subarachnoid hemorrhage. This diagnostic tool evaluates various neurological disorders, guiding critical treatment decisions.

More Related Videos

An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice

An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice

Published on: March 19, 2018

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Published on: December 4, 2017

Related Experiment Videos

Last Updated: Nov 10, 2025

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Published on: November 29, 2019

An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice

An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice

Published on: March 19, 2018

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Published on: December 4, 2017

Area of Science:

Neurology
Clinical Diagnostics
Laboratory Medicine

Background:

Cerebrospinal fluid (CSF) analysis is a crucial diagnostic method for central nervous system (CNS) disorders.
Indications include suspected infections (bacterial, viral, fungal, parasitic, tuberculosis, neurosyphilis) and subarachnoid hemorrhage (SAH).
CSF analysis also aids in evaluating conditions like multiple sclerosis, Guillain-Barré syndrome, and intracranial hypertension.

Purpose of the Study:

To highlight the diagnostic utility of cerebrospinal fluid analysis in various neurological conditions.
To emphasize the importance of timely CSF analysis for conditions with high mortality rates.
To outline key CSF findings associated with specific neurological diseases.

Main Methods:

Review of indications for lumbar puncture and CSF analysis.
Description of characteristic CSF findings in bacterial meningitis, viral meningitis, and subarachnoid hemorrhage.
Mention of adjunctive tests for meningitis differentiation and CSF cytology for leptomeningeal carcinomatosis.

Main Results:

Bacterial meningitis shows characteristic changes in white blood cell counts, protein, and glucose ratio; CSF culture identifies pathogens.
Viral meningitis may mimic bacterial meningitis but typically has lower mortality.
Subarachnoid hemorrhage diagnosis is supported by xanthochromia and elevated red blood cells in CSF, especially when imaging is equivocal or delayed.

Conclusions:

Cerebrospinal fluid analysis is indispensable for diagnosing and evaluating a spectrum of CNS diseases.
Prompt CSF analysis is vital for managing life-threatening conditions such as bacterial meningitis and subarachnoid hemorrhage.
Specific CSF biomarkers and cytology aid in differentiating infectious etiologies and identifying neoplastic spread.