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Updated: Nov 10, 2025

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
Published on: October 3, 2014
Phosphine-Catalyzed (4 + 2) Cycloaddition of Conjugated Dienes with Enones and Its Asymmetric Variant
Ke Li1, Zhenjie Gan1,2, Er-Qing Li1
1College of Chemistry, Green Catalysis Center, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University, Zhengzhou 450001, P. R. China.
Abstract:
Herein we reported a novel phosphine-catalyzed (4 + 2) cyclization reaction of electron-deficient conjugated dienes with enones to generate functionalized dihydropyran skeletons. A mechanistic investigation reveals that the reaction produces a new phosphonium zwitterion, which undergoes consecutive reactions. In addition, an asymmetric variant was developed by efficient and economical chiral phosphine catalysis.
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