Related Experiment Video
Updated: Nov 10, 2025

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data
Published on: May 16, 2022
Ensemble Linear Subspace Analysis of High-Dimensional Data
S Ejaz Ahmed1, Saeid Amiri2, Kjell Doksum3
1Department of Mathematics and Statistics, Brock University, St. Catharines, ON L2S 3A1, Canada.
Abstract:
Regression models provide prediction frameworks for multivariate mutual information analysis that uses information concepts when choosing covariates (also called features) that are important for analysis and prediction. We consider a high dimensional regression framework where the number of covariates (p) exceed the sample size (n). Recent work in high dimensional regression analysis has embraced an ensemble subspace approach that consists of selecting random subsets of covariates with fewer than p covariates, doing statistical analysis on each subset, and then merging the results from the subsets. We examine conditions under which penalty methods such as Lasso perform better when used in the ensemble approach by computing mean squared prediction errors for simulations and a real data example. Linear models with both random and fixed designs are considered. We examine two versions of penalty methods: one where the tuning parameter is selected by cross-validation; and one where the final predictor is a trimmed average of individual predictors corresponding to the members of a set of fixed tuning parameters. We find that the ensemble approach improves on penalty methods for several important real data and model scenarios. The improvement occurs when covariates are strongly associated with the response, when the complexity of the model is high. In such cases, the trimmed average version of ensemble Lasso is often the best predictor.
Related Concept Videos
Gaussian Elimination: Problem Solving
Vector Algebra: Method of Components
In many applications, the magnitudes and directions of...
Linear Approximation in Frequency Domain
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
State Space Representation
Consider an RLC circuit, a...
Linear Approximation in Time Domain
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length,...
Linear time-invariant Systems
The input-output behavior of an LTI system can be fully defined by its response to an impulsive excitation at its input. Once this impulse response is known, the system's reaction to any other input can be...

