Stimulus artifact compensation using biphasic stimulation

The feasibility of using biphasic stimulation as a method of reducing stimulus artifact was explored in several different circumstances. Sensory and muscle evoked potentials were compared using monophasic and biphasic constant-current stimuli. The monophasic stimulus was a negative rectangular pulse with a duration of 0.1-0.2 msec. The biphasic stimulus was a negative rectangular pulse of 0.1-0.2 msec duration followed, after a variable delay, by a positive rectangular pulse of the same duration and variable amplitude. When the conducting distances were long, stimulus artifact did not disturb either monophasically or biphasically evoked potentials. When the conducting distances were short, stimulus artifact occurred with monophasic stimulation but could be diminished readily using biphasic stimulation. The method can be accomplished easily using standard instruments with dual stimulators.