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Updated: Nov 8, 2025

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
Published on: July 18, 2014
The primary dipole of flipper probes
José García-Calvo1, Javier López-Andarias1, Naomi Sakai1
1Department of Organic Chemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
Abstract:
Despite their growing popularity in biology to image membrane tension, central design principles of flipper probes have never been validated. Here we report that upon deletion of their primary dipole, from electron-poor and electron-rich dithienothiophenes, absorptions blue-shift, lifetimes shorten dramatically, and mechanosensitivity in cells vanishes not partially, but completely.
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