An efficient strategy for cancer therapy using a tumor- and lysosome-targeted organic photothermal agent
Hongyu Wang1, Huiwen Zhang1, Yanan Xiang1
1College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Centre of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan, 250014, P. R. China. lina@sdnu.edu.cn tangb@sdnu.edu.cn.
Abstract:
A dual-targeted organic photothermal agent for tumor cells and lysosomes was developed. In vitro and in vivo experiments demonstrated that it possessed low cytotoxicity, good biological compatibility, and tumor inhibitory effects.
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