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[Renal cell carcinoma in the solitary kidney]
1Department of Urology, School of Medicine, University of Tokushima.
Abstract:
We have treated surgically 5 patients with renal cell carcinoma in the solitary kidney. The cause of renal absence was nephrectomy for renal stones, in 2 patients and renal tuberculosis, renal cyst and renal hypoplasia in 1 patient each. Four of the 5 patients died. One of the 4 patients died 5 days after surgery due to gastrointestinal bleeding, 1 due to metastasis, 1 due to gastric cancer and one due to hemodialysis complications. Surgical management of renal cell carcinoma of solitary kidney is discussed.
Insights
Treating renal cell carcinoma in a solitary kidney poses significant risks. This study highlights a high mortality rate following surgical intervention for these rare cases.
Area of Science:
- Nephrology
- Oncology
- Surgical Oncology
Background:
- Renal cell carcinoma (RCC) in a solitary kidney is a rare clinical scenario.
- Patients with a solitary kidney present unique challenges for surgical management.
- Causes of solitary kidney included prior nephrectomy, renal tuberculosis, cyst, or hypoplasia.
Observation:
- Five patients with renal cell carcinoma in a solitary kidney underwent surgical treatment.
- The cohort included diverse etiologies for the solitary kidney, primarily prior nephrectomy for stones.
Findings:
- Four out of five patients (80%) died post-surgery.
- Mortality causes included early gastrointestinal bleeding, metastatic disease, gastric cancer, and complications of hemodialysis.
- The high mortality underscores the aggressive nature and poor prognosis associated with this condition.
Implications:
- Surgical management of renal cell carcinoma in a solitary kidney is associated with a high mortality rate.
- Careful patient selection and consideration of alternative treatment modalities are crucial.
- Further research is needed to optimize treatment strategies for this challenging patient group.