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Related Experiment Video

Updated: Nov 4, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Mature Orbital Teratoma.

Rabia Chaudhry1, M Nasar Qamar1, Areej Riaz1

  • 1Department of Ophthalmology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|May 24, 2021
PubMed
Summary

Orbital teratoma, a rare congenital tumor, can rapidly threaten infant vision. Surgical removal of this mature teratoma in an infant achieved good cosmetic results, though vision was not preserved.

Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Surgical Pathology

Background:

  • Orbital teratomas are rare congenital tumors originating from all three germ cell layers.
  • These tumors present in neonates with unilateral proptosis, potentially leading to optic nerve compromise and vision loss.
  • While mature teratomas are benign, immature teratomas carry a risk of malignant transformation.

Observation:

  • A six-month-old female infant presented with a mature orbital teratoma present since birth.
  • The tumor caused rapid proptosis, compromising vision.
  • Globe conservation was challenging due to the advanced stage of the tumor.

Findings:

  • Complete surgical excision of the mature orbital teratoma was performed.
  • Despite complete removal, vision could not be salvaged in the affected eye.

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  • Excellent cosmetic outcomes were achieved post-surgery.

    • Implications:

    • This case highlights the challenges in managing congenital orbital teratomas, particularly regarding vision preservation.
    • Complete surgical excision is crucial for achieving good cosmetic results and preventing malignant transformation.
    • Early diagnosis and intervention may be critical, though challenging in congenital cases.