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Towards a molecular mechanism for the crossbridge cycle
J S Wray1, R S Goody, K C Holmes
1Abteilung Biophysik, Max-Planck-Institut für Medizinische Forschung, Heidelberg, F.R.G.
Advances in Experimental Medicine and Biology
|January 1, 1988
Abstract:
Present evidence on crossbridge behaviour is reviewed from the viewpoint of the Eisenberg-Hill concepts. We conclude that a cartoon illustrating the operation of these ideas in practice should be drawn so as to include morphological changes in the body of the myosin molecule as part of the power-stroke. The bulk of structural evidence on the operation of crossbridges in intact muscle supports such a description.