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Vancomycin-Functionalized Porphyrinic Metal-Organic Framework PCN-224 with Enhanced Antibacterial Activity against
Li-Jian Chen1,2, Yao-Yao Liu1,2, Xu Zhao1,2
1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.
Chemistry, an Asian Journal
|June 7, 2021
Abstract:
A vancomycin (Van) modification strategy on a porphyrinic metal-organic framework (MOF) PCN-224 is presented. The obtained Van-PCN-224 gives the combined advantages of porphyrinic MOF and Van with high photosensitive activity and excellent targeted antibacterial activity against Staphylococcus aureus. The features make Van-PCN-224 promising for antimicrobial therapy.
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