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The Pituitary Tumors and Their Tumor-Specific Microenvironment
1Departments of Surgery, Division of Neurosurgery, McMaster University, Hamilton General Hospital, Hamilton, ON, Canada. michelle.kameda@medportal.ca.
Abstract:
Pituitary tumors develop within a macroenvironment and microenvironment that favor their overall survival. Given the pituitary gland's unique anatomic, histological, and physiological properties, the role of the TME in the pituitary tumors is central. This chapter summarizes the body of literature investigating the role of each component of the TME in relation to tumors of the pituitary and its intimate association with tumorigenesis, maintenance, and progression.
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