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Huge Lateral Rectus Solitary Plasmacytoma Causing Shunt Extrusion
Nikoo Hamzeh1, Mona Safizadeh2, Zohreh Nozarian3
1Orbital and Oculoplastics Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Case Reports in Ophthalmological Medicine
|July 1, 2021
Summary
A recurrent orbital plasmacytoma caused progressive proptosis and vision loss. Surgical resection and radiotherapy led to complete remission of this rare orbital tumor.
Area of Science:
- Oncology
- Ophthalmology
- Pathology
Background:
- Plasmacytoma is a rare plasma cell neoplasm.
- Orbital involvement can lead to significant visual morbidity.
- Previous radiotherapy for maxillary sinus plasmacytoma increases recurrence risk.
Observation:
- A 54-year-old man presented with progressive proptosis and vision loss in his right eye.
- Imaging revealed a large orbital mass involving the lateral rectus muscle.
- History of radiotherapy for maxillary sinus plasmacytoma and prior ocular surgeries for neovascular glaucoma secondary to central retinal vein occlusion (CRVO).
Findings:
- Pathology confirmed orbital plasmacytoma with anaplastic features.
- Surgical tumor resection improved symptoms.
- Post-operative radiotherapy resulted in complete remission.
Implications:
- This case highlights the potential for late recurrence of plasmacytoma in the orbit.
- Anaplastic features may indicate a more aggressive tumor behavior.
- Multimodal treatment including surgery and radiotherapy is crucial for managing orbital plasmacytoma.

