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Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
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Nanoprecipitation as a simple and straightforward process to create complex polymeric colloidal morphologies.
Xibo Yan1, Julien Bernard2, François Ganachaud2
1School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Advances in Colloid and Interface Science
|July 26, 2021
Summary
The nanoprecipitation technique offers precise control over creating diverse polymeric nanoparticles with varied internal structures. This method enables the fabrication of complex nanostructures for numerous applications.
Area of Science:
- Materials Science
- Nanotechnology
- Polymer Chemistry
Background:
- Polymeric nanoparticles are crucial functional nanomaterials with broad applications in therapeutics and energy.
- Nanotechnology advancements allow for the engineering of multifunctional polymeric nanoparticles with diverse shapes and morphologies.
Purpose of the Study:
- To review the capability of the nanoprecipitation technique for fabricating polymeric nanostructures.
- To highlight the control over nanostructure afforded by this method.
Main Methods:
- The review focuses on the nanoprecipitation technique for synthesizing polymeric nanoparticles.
- This includes the precipitation of block copolymers and homopolymer mixtures.
Main Results:
- Nanoprecipitation allows precise control over nanostructure formation, yielding various morphologies like onion-like, stacked lamellae, and porous cores.
- Core-shell structures from polymer or oil/polymer mixtures are achievable via this one-pot process.
Conclusions:
- The nanoprecipitation technique is a versatile and simple method for creating complex polymeric nanostructures.
- Future research directions aim to expand the scope and applications of this fabrication process.
