Nanobiotechnology enabled approaches for wastewater based epidemiology

Area of Science:

• Environmental Science
• Biotechnology
• Public Health

Background:

• The COVID-19 pandemic underscored the need for robust environmental monitoring systems.
• Wastewater-based epidemiology (WBE) has emerged as a critical tool for analyzing public health indicators.
• Field-deployable analytical tools are essential for real-time WBE implementation.

Purpose of the Study:

• To review the design and working principles of nanobiotechnology-enabled biosensors.
• To highlight recent advancements in biosensor applications for biomarker detection.
• To discuss the potential of biosensors for SARS-CoV-2 monitoring within WBE.

Main Methods:

• Review of scientific literature on nanobiotechnology-enabled biosensors.
• Analysis of biosensor design, working principles, and detection capabilities.
• Examination of current and potential applications in wastewater-based epidemiology.

Main Results:

• Nanobiotechnology offers highly efficient and sensitive biosensing platforms.
• Biosensors show promise for detecting various biomarkers, including SARS-CoV-2.
• These platforms are crucial for advancing real-time WBE.

Conclusions:

• Nanobiotechnology-enabled biosensors are vital for expanding WBE capabilities.
• Further development is needed to address challenges in real-world WBE applications.
• Biosensors hold significant potential for monitoring future public health threats.