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Updated: Oct 26, 2025

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Waterpipe Tobacco Warnings Need to Inform Users of Harm
Mohammed Moumen1, Marielle Brinkman1, Brittney Keller-Hamilton1
1Mohammed Moumen, Medical Student, Wake Forrest School of Medicine, Winston-Salem, NC. Marielle Brinkman, Senior Research Scientist, Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH. Brittney Keller-Hamilton, Research Scientist, Comprehensive Cancer Center, The Ohio State University, Columbus, OH. Andreas A. Teferra, Doctoral Student, Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH. Megan E. Roberts, Assistant Professor, Division of Health Behavior and Health Promotion, College of Public Health, The Ohio State University, Columbus, OH. Elizabeth G. Klein, Interim Chair and Associate Professor, Division of Health Behavior and Health Promotion, College of Public Health, The Ohio State University, Columbus, OH. Paul Nini, Professor, Department of Design, College of Arts and Sciences, The Ohio State University, Columbus, OH. Michael Pennell, Associate Professor, Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH. Amy K. Ferketich, Professor Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.
Objectives:
Health warning messages could be an effective means of communicating the health risks associated with waterpipe (WP) smoking. The objective of this study was to select a message that conveyed the risks associated with WP smoking.
Methods:
A mixed-methods approach was used to explore the effectiveness of the Food and Drug Administration's (FDA's) mandated message, and others, among young adults using focus groups and surveys. Two focus group studies and one convenience survey were conducted to examine the FDA's mandated message and 11 other WP warning messages. The final study, conducted with a random sample of first-year university students, examined the effectiveness and reactance of the chosen message using previously validated items (scored on a 1-5 scale).
Results:
The FDA's mandated message did not resonate well with focus group participants. In the random sample of students, the top message (WARNING: Hookah smoke contains poisons that cause lung and oral cancers) had high effectiveness (M = 4.49) and a low reactance (M = 2.12).
Conclusions:
Our studies suggest that other messages are more effective for communicating the risks associated with WP smoking than the FDA's message for WP tobacco.
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