Individual (Co)variation in Resting and Maximal Metabolic Rates in Wild Mice

AbstractBasal metabolic rate (BMR) represents the lowest level of aerobic metabolism in a resting, postabsorptive endotherm as measured within the thermoneutral zone. By contrast, maximal metabolic rate ([Formula: see text]max) reflects the upper limit of aerobic metabolism achieved during intensive exercise. As BMR and [Formula: see text]max define the boundaries of the possible levels of aerobic metabolism expressed by a normothermic individual, a key question is whether BMR and [Formula: see text]max are correlated. In the present study, we took repeated paired measurements of thermoneutral resting metabolic rate (RMR_t) and [Formula: see text]max on 165 white-footed mice (Peromyscus leucopus). Over a single summer (May-October), repeatability (R ± SE) was low but statistically significant ([Formula: see text]) for both RMR_t and [Formula: see text]max ([Formula: see text] for RMR_t; [Formula: see text] for [Formula: see text]max). Willingness to run during the forced-exercise trials was also significantly repeatable ([Formula: see text]). At the residual level (within individual), RMR_t and [Formula: see text]max tended to be positively correlated ([Formula: see text], [Formula: see text]), suggesting the presence of correlated phenotypic plasticity. By contrast, RMR_t and [Formula: see text]max were significantly negatively correlated at the among-individual level ([Formula: see text]). To the extent that variation in RMR_t reflects variation in BMR, the negative among-individual correlation does not corroborate the idea that a costly metabolic machinery is needed to support a high [Formula: see text]max. Future research should investigate the (genetic) relationship between RMR_t (and BMR) and other energetically expensive behaviors and activities to better understand how energy is allocated within individuals.